As a send-off for the cartoonist, the satirical publication has prepared an all-Jaffee issue that includes his final Fold-In.

Fun fact! The fold-in concept Al Jaffee came up with in 1964 on the back pages of MAD was a satirical take on the centrefolds of the 60s Playboys and other rags.

Source: At 99, Al Jaffee Says Goodbye to Mad Magazine (NYT)